Dad dot info
DAD.info form. Ask questions, get answers

Doctors hope new bacteria-containing nose drops will help prevent meningitis

Doctors have created a nose drop containing a type of “friendly” bacteria which they hope could help prevent meningitis and other infections

 

In a previous study, the research team found inoculating adults with a “friendly” bacterial strain, known as Neisseria lactamica (Nlac), which is a close cousin of N. meningitidis, resulted in Nlac settling harmlessly in the nose for months and prevented them carrying N. meningitidis at the same time.

They now hope genetically enhancing the bacteria with a “sticky” surface protein from N.meningitidis will increase the ability of Nlac to reside in the nose and generate a strong immune response that protects against the meningitis-causing bacteria.

Prof Read said: “We have already shown that placing Nlac in the nose of healthy adults caused no harm to the volunteers, the bacteria settled and it caused an immune response which we believe could prevent the acquisition of harmful bacteria.

“Now, following extensive work in the laboratory, we have developed a nose drop which includes Nlac that has been enhanced with a gene to help broaden its effect to, we hope, exclude N. meningitidis.”

Prof Read added that, if successful, he hoped the technique could be used to prevent other infections such as pneumonia and ear disease.

The research team has applied to the Department for Environment, Food and Rural Affairs (Defra) for permission to use the genetically-modified drop in volunteers prior to launching the clinical trials.

Meningococcal meningitis, which is a bacterial form of the disease and is responsible for 1,500 cases a year in the UK, can cause death in as little as four hours from the onset of symptoms.

Related entries

Your Guide to the European Championships

Your Guide to the European Championships

Like it or loathe it, the next few weeks are going to be all about football. If you want the basics to keep up with your footy crazy kids we’ve compiled this handy guide to give you an overview of the upcoming European Championships. UEFA.com What are the European...

The Duke and Duchess of Sussex welcome a new baby girl

The Duke and Duchess of Sussex welcome a new baby girl

Welcome to the world Baby Lilibet. The Dad.info team loves a baby and the new daughter of the Duke and Duchess of Sussex is just the good news we need. https://twitter.com/RoyalFamily/status/1401614927236841474 Named for her grandmother and great-grandmother, Lilibet...

Latest entries

How To Keep Your Child Safe Online

How To Keep Your Child Safe Online

As a parent of a 10 year old who is rapidly approaching the age where he will be getting his own phone, I’m concerned about ensuring he isn’t exposed to a cavalcade of disturbing things online. I’m worrying about bullying, about him being contacted or making friends...

21 Things You Didn’t Know About Japan

21 Things You Didn’t Know About Japan

The Olympics have started! Despite a lack of fans (crowd noise will be piped into the stadiums instead) the event is still as important as ever and makes for great summer viewing. So at Dad.Info we have rounded up 21 interesting facts about Japan to both liberally...

How To Have A Holiday At Home

How To Have A Holiday At Home

If you’re anything like me and flip flopped about for ages, unsure what to do about booking a summer holiday this year amid constantly- changing Covid news, then you’ll be finding yourself at home for the summer. But while we may not be able to dip our toes in the...

Pin It on Pinterest